Abstract The effect of mechanical properties of erythrocytes on the near-wall motion of platelets was numerically studied with the immersed boundary method. Cells were modeled as viscous-fluid-filled capsules surrounded by hyper-elastic membranes with negligible thickness. The numerical results show that with the increase of hematocrit, the near-wall approaching of platelets is enhanced, with which platelets exhibit larger deformation and orientation angle of its near-wall tank-treading motion, and the lateral force pushing platelets to the wall is increased with larger fluctuation amplitude. Meanwhile the near-wall approaching is reduced by increasing the stiffness of erythrocytes.
Received: 14 June 2013
Published: 02 December 2013
Fund:The project was supported by the National Natural Science Foundation of China (11072155 and 11232010) and Doctoral Fund of Ministry of Education of China (20100073120009).
Corresponding Authors:
Xiao-Bo Gong
E-mail: x.gong@sjtu.edu.cn
Cite this article:
Jing Xu,Xiao-Long Wang,Yun-Qiao Liu et al. A cellular scale numerical study of the effect of mechanical properties of erythrocytes on the near-wall motion of platelets[J]. Acta Mechanica Sinica, 2014, 30(2): 274-280.
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